By John Maas, DVM, MS
Diplomate, ACVN & ACVIM
Extension Veterinarian
School of Veterinary Medicine
University of California-Davis
Description and Cause
Copper deficiency in beef cattle has been recognized more commonly in California. Copper deficiency causes significant economic losses where it occurs. Copper deficiency in cattle is complicated because it can be the result of:
very low copper in the diet-a primary copper deficiency, or
interference with copper absorption in the animal due to molybdenum and/or sulfates in the food or water-a secondary copper deficiency.
Regardless of the reason for the copper deficiency, the problems exhibited by the animals are the same. Some of the common symptoms seen in cattle with copper deficiency include:
diarrhea,
unthrifty appearance,
poor weight gains,
light hair coats (angus are grey, Herefords are yellow),
swollen, painful joints,
broken bones,
rear leg weakness of paralysis in calves,
infertility,
anemia,
and decreased resistance to disease.
The problems seen will vary from herd to herd and are not easily predictable. However, when copper deficiency does occur, it invariably causes losses in production, health, and profits.
The fact that copper deficiency lowers the immune response and can make the cattle more suspectable to disease and less responsive to vaccines is of particular importance to the health of the herd
What diseases are associated with Copper?
A short course designed by Murdoch University and The University of Sydney.
Sponsored by Grant 1034/25 from the Committee for the Advancement of University Teaching
(CAUT)1995.
WHAT DISEASE STATES OCCUR WITH DEFICIENCY?
OF COPPER?
Copper deficiency during pregnancy can result in the birth of offspring with congenital disease of the nervous system. This situation is most common in lambs. In addition neonatal lambs, apparently normal at birth, often express neurologic disease at any time between 1 week and several months of age.
1) There are a number of severe effects on nerve cells and myelin, in which destructive changes range from degeneration of neurons and axons within intact supporting tissues, to wholesale loss of all nervous tissue components, with resulting cavitation (in lambs) of some areas of cerebral white matter. Neural degeneration may extend widely throughout the brain, spinal cord and peripheral nerves.
2) In the delayed disease there are no macroscopically visible changes, but the microscope reveals swollen and dying nerve cells in many parts of the brain and spinal cord (JKP Fig. 3.16), together with disintegrating myelinated axons in parts of the brain and cord (JKP Fig. 3.22A) and in spinal motor nerves (JKP Fig. 3.21). The changes in goat kids and piglets are essentially similar, but with some differences which need not concern us here.
In the bones, there is production of thin trabeculae, with abnormally fragile and thin metaphyseal and diaphyseal bone. This state is called osteoporosis and can result in bowing of long bones, metaphyseal enlargement, and spontaneous fractures
In the bone marrow there is ineffective production and output of red blood cells in spite of an increased number (hyperplasia) of precursor cells. Consequentially there will be reduced numbers of circulating erythrocytes, and a reduced concentration of haemoglobin in the blood, producing a state of anaemia
Problems Which Can Frequently Be Related to Nutrition
Originally published in Agribusiness Dairyman
Reprinted in REDGA Goat Notes & United Caprine News ('96)
Paralytic Problems:
Problems: Possible nutritional answers:
Milk FeverCa/Phos. Ratio; Vit. D; inorganic sulfate
Downer milk fever The above + magnesium
Grass tetany Magnesium
Knuckling fetlocks, weak hindlegs Vitamin E, Selenium, Copper
Nerve loss Copper
Ataxia Copper, copper-molybdenum
Breeding Problems:
Problems: Possible nutritional answers:
Retained placentas, metritis Copper, zinc, selenium, vitamin E
Lack of estrus Copper, zinc, selenium, vitamin E
Tailess sperm in semen Selenium
Lack of libido Copper-molybdenum
Hoof Problems:
Problems: Possible nutritional answers:
Hoof Rot Copper, iodine
Abnormal hoof growth Copper
Soft hoof growth Copper
Swollen fetlocks Copper
Laminitis High rumen acid upsets copper absorption
Hairy wart resistance Copper (nutrition), formaldehyde (foot bath)
Intestinal Problems:
Problems: Possible nutritional answers:
Acidosis (pH balance)Sodium bicarbonate
Low butterfat test Sodium bicarbonate
Undigested feed in manure Copper, cobalt
Scouring Copper, molybdenum
Worm resistance Copper, molybdenum
Low production Copper, zinc, manganeses, inorganic sulfate
Abnormal appetite Copper, cobalt
Metabolic Problems:
Problems: Possible nutritional answers:
High somatic cell count Copper, zinc, selenium, Vitamin E
Ketosis Copper, inorganic sulfate
White muscle disease Selenium
Pneumonia Copper, zinc, selenium, Vitamin E
Heart abnormalities Copper, selenium, magnesium
Anemia Iron, copper, cobalt
Tongue lolling Copper
Retarded growth Copper, molybdenum
Sudden death Copper, selenium, grease & nitrate
Off-flavor milk High iron (feed or water; Vitamin E
High culling rate Poor mineral nutrition program
Fat cow syndrome Copper, inorganic sulfate
Hair off color, no bloom Copper, selenium
